Cargando…

NuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions

The epidermis is a multilayered epithelium that requires asymmetric divisions for stratification. A conserved cortical protein complex, including LGN, nuclear mitotic apparatus (NuMA), and dynein/dynactin, plays a key role in establishing proper spindle orientation during asymmetric divisions. The r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seldin, Lindsey, Poulson, Nicholas D., Foote, Henry P., Lechler, Terry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842992/ https://www.ncbi.nlm.nih.gov/pubmed/24109598 http://dx.doi.org/10.1091/mbc.E13-05-0277

Ejemplares similares

NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
por: Seldin, Lindsey, et al.
Publicado: (2016)

Plk1 regulates spindle orientation by phosphorylating NuMA in human cells
por: Sana, Shrividya, et al.
Publicado: (2018)

SLK-dependent activation of ERMs controls LGN–NuMA localization and spindle orientation
por: Machicoane, Mickael, et al.
Publicado: (2014)

Requirements for NuMA in maintenance and establishment of mammalian spindle poles
por: Silk, Alain D., et al.
Publicado: (2009)

NuMA phosphorylation dictates dynein-dependent spindle positioning
por: Kotak, Sachin, et al.
Publicado: (2014)

Pinning down NuMA
por: Wells, William A.
Publicado: (2001)

NuMA is required for proper spindle assembly and chromosome alignment in prometaphase
por: Haren, Laurence, et al.
Publicado: (2009)

Regulation of mitotic spindle assembly factor NuMA by Importin-β
por: Chang, Chih-Chia, et al.
Publicado: (2017)

Spindle pole cohesion requires glycosylation-mediated localization of NuMA
por: Magescas, Jérémy, et al.
Publicado: (2017)

Aurora A phosphorylates Ndel1 to reduce the levels of Mad1 and NuMA at spindle poles
por: Janczyk, Paweł Ł., et al.
Publicado: (2022)

NuMA forms condensates through phase separation to drive spindle pole assembly
por: Ma, Huixian, et al.
Publicado: (2021)

NuMA is required for the proper completion of mitosis
Publicado: (1993)

NuMA Overexpression in Epithelial Ovarian Cancer
por: Brüning-Richardson, Anke, et al.
Publicado: (2012)

A Nonerythroid Isoform of Protein 4.1R Interacts with the Nuclear Mitotic Apparatus (NuMA) Protein
por: Mattagajasingh, Subhendra N., et al.
Publicado: (1999)

The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics
por: Serra-Marques, Andrea, et al.
Publicado: (2020)

NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation
por: Sun, Mengjie, et al.
Publicado: (2021)

NMR characterisation of the minimal interacting regions of centrosomal proteins 4.1R and NuMA1: effect of phosphorylation
por: Treviño, Miguel A, et al.
Publicado: (2010)

p37/UBXN2B regulates spindle orientation by limiting cortical NuMA recruitment via PP1/Repo-Man
por: Lee, Byung Ho, et al.
Publicado: (2018)

Comprehensive analysis of NuMA variation in breast cancer
por: Kilpivaara, Outi, et al.
Publicado: (2008)

The Nuclear Mitotic Apparatus (NuMA) Protein: A Key Player for Nuclear Formation, Spindle Assembly, and Spindle Positioning
por: Kiyomitsu, Tomomi, et al.
Publicado: (2021)

Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans
por: Portegijs, Vincent, et al.
Publicado: (2016)

Robust control of mitotic spindle orientation in the developing epidermis
por: Poulson, Nicholas D., et al.
Publicado: (2010)

Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
por: Okumura, Masako, et al.
Publicado: (2018)

Regulated spindle orientation buffers tissue growth in the epidermis
por: Morrow, Angel, et al.
Publicado: (2019)

Num1 versus NuMA: insights from two functionally homologous proteins
por: Greenberg, Samuel R., et al.
Publicado: (2018)

NuMA1 promotes axon initial segment assembly through inhibition of endocytosis
por: Torii, Tomohiro, et al.
Publicado: (2019)

NuMA is required for the organization of microtubules into aster-like mitotic arrays
Publicado: (1995)

NuMA recruits dynein activity to microtubule minus-ends at mitosis
por: Hueschen, Christina L, et al.
Publicado: (2017)

A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells
por: Peyre, Elise, et al.
Publicado: (2011)

IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles
por: Taulet, Nicolas, et al.
Publicado: (2019)

NuMA1 facilitates the assembly of the axon initial segment by promoting the retention of neurofascin-186
por: Abouelezz, Amr, et al.
Publicado: (2020)

NuMA: an unusually long coiled-coil related protein in the mammalian nucleus
Publicado: (1992)

Circulation autoantibodies against C-terminus of NuMA in patients with Behçet’s disease
por: HUSSAIN, MUHAMMAD, et al.
Publicado: (2020)

NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit
por: Rajeevan, Ashwathi, et al.
Publicado: (2020)

Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics
por: Jin, Mingyue, et al.
Publicado: (2017)

Cell cycle–regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation
por: Zheng, Zhen, et al.
Publicado: (2014)

Par1b links lumen polarity with LGN–NuMA positioning for distinct epithelial cell division phenotypes
por: Lázaro-Diéguez, Francisco, et al.
Publicado: (2013)

Membrane compartmentalization of Ect2/Cyk4/Mklp1 and NuMA/dynein regulates cleavage furrow formation
por: Sana, Shrividya, et al.
Publicado: (2022)

Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis
Publicado: (1992)

On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN
por: Mapelli, Marina, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m3qc6kr3hb6vj9i18h0dvtd24g