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αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors

The actin-binding protein αE-catenin may contribute to transitions between cell migration and cell–cell adhesion that depend on remodeling the actin cytoskeleton, but the underlying mechanisms are unknown. We show that the αE-catenin actin-binding domain (ABD) binds cooperatively to individual actin...

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Detalles Bibliográficos
Autores principales: Hansen, Scott D., Kwiatkowski, Adam V., Ouyang, Chung-Yueh, Liu, HongJun, Pokutta, Sabine, Watkins, Simon C., Volkmann, Niels, Hanein, Dorit, Weis, William I., Mullins, R. Dyche, Nelson, W. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842997/
https://www.ncbi.nlm.nih.gov/pubmed/24068324
http://dx.doi.org/10.1091/mbc.E13-07-0388