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CYP2D6 P34S Polymorphism and Outcomes of Escitalopram Treatment in Koreans with Major Depression

OBJECTIVE: Cytochrome P450 (CYP) enzymatic activity, which is influenced by CYP genetic polymorphism, is known to affect the inter-individual variation in the efficacy and tolerability of antidepressants in major depressive disorder (MDD). Escitalopram is metabolized by CYP2D6, and recent studies ha...

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Detalles Bibliográficos
Autores principales: Han, Kyu-Man, Chang, Hun Soo, Choi, In-Kwang, Ham, Byung-Joo, Lee, Min-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843022/
https://www.ncbi.nlm.nih.gov/pubmed/24302953
http://dx.doi.org/10.4306/pi.2013.10.3.286