A comparative study on the anti-inflammatory effects of single oral doses of naproxen and its hydrogen sulfide (H(2)S)-releasing derivative ATB-346 in rats with carrageenan-induced synovitis

BACKGROUND: Non-steroidal antiinflammatory drugs (NSAIDs) are the most commonly prescribed agents for arthritic patients, although gastric effects limit their long-term use. Considering the reported gastric safety of hydrogen sulfide (H(2)S)-releasing NSAIDs, in addition to the anti-inflammatory eff...

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Detalles Bibliográficos
Autores principales: Ekundi-Valentim, Eduardo, Mesquita, Filiphe PN, Santos, Karen T, de Paula, Marco A Vieira, Florenzano, Juliana, Zanoni, Cristiane I, Rodrigues, Leandro, de Nucci, Gilberto, Teixeira, Simone A, Ferreira, Heloisa HA, Wallace, John L, Costa, Soraia KP, Muscará, Marcelo N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843537/
https://www.ncbi.nlm.nih.gov/pubmed/24237604
http://dx.doi.org/10.1186/2045-9912-3-24

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