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Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate diverse cellular processes including proliferation, adhesion, survival, and motility. Dysregulated PI3K pathway signaling occurs in one-third of human tumors. Aberrantly activated PI3K signaling also confers sensitivity and resis...

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Detalles Bibliográficos
Autores principales:	Akinleye, Akintunde, Avvaru, Parthu, Furqan, Muhammad, Song, Yongping, Liu, Delong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843585/ https://www.ncbi.nlm.nih.gov/pubmed/24261963 http://dx.doi.org/10.1186/1756-8722-6-88

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