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Development of a steady-state FRET-based assay to identify inhibitors of the Keap1-Nrf2 protein–protein interaction
One of the strategies proposed for the chemoprevention of degenerative diseases and cancer involves upregulation of antioxidant and free radical detoxification gene products by increasing the intracellular concentration of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2)....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843635/ https://www.ncbi.nlm.nih.gov/pubmed/24130096 http://dx.doi.org/10.1002/pro.2384 |