mtDNA T8993G Mutation-Induced F1F0-ATP Synthase Defect Augments Mitochondrial Dysfunction Associated with hypoxia/reoxygenation: The Protective Role of Melatonin

BACKGROUND: F1F0-ATP synthase (F1F0-ATPase) plays important roles in regulating mitochondrial function during hypoxia, but the effect of F1F0-ATPase defect on hypoxia/reoxygenation (H/RO) is unknown. The aim of this study was to investigate how mtDNA T8993G mutation (NARP)-induced inhibition of F1F0...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Wen-Yi, Jou, Mei-Jie, Tsung, I. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843685/
https://www.ncbi.nlm.nih.gov/pubmed/24312318
http://dx.doi.org/10.1371/journal.pone.0081546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843685/
https://www.ncbi.nlm.nih.gov/pubmed/24312318
http://dx.doi.org/10.1371/journal.pone.0081546

Ejemplares similares