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Conformational Polymorphism of m(7)GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus

Influenza pandemics with human-to-human transmission of the virus are of great public concern. It is now recognized that a number of factors are necessary for human transmission and virulence, including several key mutations within the PB2 subunit of RNA-dependent RNA polymerase. The structure of th...

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Detalles Bibliográficos
Autores principales:	Tsurumura, Toshiharu, Qiu, Hao, Yoshida, Toru, Tsumori, Yayoi, Hatakeyama, Dai, Kuzuhara, Takashi, Tsuge, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843726/ https://www.ncbi.nlm.nih.gov/pubmed/24312396 http://dx.doi.org/10.1371/journal.pone.0082020

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