The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages()

Agglomeration dramatically affects many aspects of nanoparticle–cell interactions. Here we show that hydroxyapatite nanoparticles formed large agglomerates in biological medium resulting in extensive particle uptake and dose-dependent cytotoxicity in human macrophages. Particle citration and/or the...

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Detalles Bibliográficos
Autores principales: Müller, Karin H., Motskin, Michael, Philpott, Alistair J., Routh, Alexander F., Shanahan, Catherine M., Duer, Melinda J., Skepper, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843813/
https://www.ncbi.nlm.nih.gov/pubmed/24183166
http://dx.doi.org/10.1016/j.biomaterials.2013.10.041

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