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Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report

Growing teratoma syndrome (GTS) is defined as metastatic masses during or after chemotherapy for germ cell tumors, which contain only mature teratoma components. The peritoneum of the pelvis and abdomen and the retroperitoneum are the most frequent sites of metastasis. We report a case of GTS of the...

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Autores principales: Shibata, Kiyosumi, Kajiyama, Hiroaki, Kikkawa, Fumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843913/
https://www.ncbi.nlm.nih.gov/pubmed/24348391
http://dx.doi.org/10.1159/000356563
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author Shibata, Kiyosumi
Kajiyama, Hiroaki
Kikkawa, Fumitaka
author_facet Shibata, Kiyosumi
Kajiyama, Hiroaki
Kikkawa, Fumitaka
author_sort Shibata, Kiyosumi
collection PubMed
description Growing teratoma syndrome (GTS) is defined as metastatic masses during or after chemotherapy for germ cell tumors, which contain only mature teratoma components. The peritoneum of the pelvis and abdomen and the retroperitoneum are the most frequent sites of metastasis. We report a case of GTS of the ovary showing three patterns of metastasis: dissemination, lymphogenous metastasis, and hematogenous metastasis. The patient initially presented 5 years ago with a mixed germ cell tumor of the left ovary and positive cytology of ascites. After surgery and chemotherapy, mature teratomas recurred as pelvic peritoneal dissemination, a para-aortic lymph node mass, and a lung mass. Our case highlights the importance of long-term follow-up and a whole-body search. We think that our case is suggestive regarding the mechanism of critical GTS.
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spelling pubmed-38439132013-12-12 Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report Shibata, Kiyosumi Kajiyama, Hiroaki Kikkawa, Fumitaka Case Rep Oncol Published online: November, 2013 Growing teratoma syndrome (GTS) is defined as metastatic masses during or after chemotherapy for germ cell tumors, which contain only mature teratoma components. The peritoneum of the pelvis and abdomen and the retroperitoneum are the most frequent sites of metastasis. We report a case of GTS of the ovary showing three patterns of metastasis: dissemination, lymphogenous metastasis, and hematogenous metastasis. The patient initially presented 5 years ago with a mixed germ cell tumor of the left ovary and positive cytology of ascites. After surgery and chemotherapy, mature teratomas recurred as pelvic peritoneal dissemination, a para-aortic lymph node mass, and a lung mass. Our case highlights the importance of long-term follow-up and a whole-body search. We think that our case is suggestive regarding the mechanism of critical GTS. S. Karger AG 2013-11-05 /pmc/articles/PMC3843913/ /pubmed/24348391 http://dx.doi.org/10.1159/000356563 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: November, 2013
Shibata, Kiyosumi
Kajiyama, Hiroaki
Kikkawa, Fumitaka
Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title_full Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title_fullStr Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title_full_unstemmed Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title_short Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
title_sort growing teratoma syndrome of the ovary showing three patterns of metastasis: a case report
topic Published online: November, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843913/
https://www.ncbi.nlm.nih.gov/pubmed/24348391
http://dx.doi.org/10.1159/000356563
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