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Life-Threatening Gastrointestinal Mucosal Necrosis during Methotrexate Treatment for Rheumatoid Arthritis

Methotrexate (MTX), a folic acid antagonist, is widely used in the treatment of neoplasms, psoriasis and rheumatoid arthritis. Despite its efficacy, MTX sometimes finds limited application because of its adverse effects, including renal or liver impairment, bone marrow toxicity and gastrointestinal...

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Detalles Bibliográficos
Autores principales: Tsukada, Tomoya, Nakano, Tatsuo, Miyata, Takashi, Sasaki, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843920/
https://www.ncbi.nlm.nih.gov/pubmed/24348319
http://dx.doi.org/10.1159/000356817