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Mouse Paneth cell antimicrobial function is independent of Nod2

OBJECTIVE: Although polymorphisms of the NOD2 gene predispose to the development of ileal Crohn's disease, the precise mechanisms of this increased susceptibility remain unclear. Previous work has shown that transcript expression of the Paneth cell (PC) antimicrobial peptides (AMPs) α-defensin...

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Detalles Bibliográficos
Autores principales:	Shanahan, Michael T, Carroll, Ian M, Grossniklaus, Emily, White, Andrew, von Furstenberg, Richard J, Barner, Roshonda, Fodor, Anthony A, Henning, Susan J, Sartor, R Balfour, Gulati, Ajay S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2014
Materias:	Inflammatory Bowel Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844066/ https://www.ncbi.nlm.nih.gov/pubmed/23512834 http://dx.doi.org/10.1136/gutjnl-2012-304190

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