Dynamic response to peripheral nerve injury detected by in situ hybridization of IL-6 and its receptor mRNAs in the dorsal root ganglia is not strictly correlated with signs of neuropathic pain

BACKGROUND: IL-6 is a typical injury-induced mediator. Together with its receptors, IL-6 contributes to both induction and maintenance of neuropathic pain deriving from changes in activity of primary sensory neurons in dorsal root ganglia (DRG). We used in situ hybridization to provide evidence of I...

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Detalles Bibliográficos
Autores principales: Brázda, Václav, Klusáková, Ilona, Hradilová Svíženská, Ivana, Dubový, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844395/
https://www.ncbi.nlm.nih.gov/pubmed/23953943
http://dx.doi.org/10.1186/1744-8069-9-42

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