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Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons

BACKGROUND: Myelinated axons are organized into distinct subcellular and molecular regions. Without proper organization, electrical nerve conduction is delayed, resulting in detrimental physiological outcomes. One such region is the paranode where axo-glial septate junctions act as a molecular fence...

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Detalles Bibliográficos
Autores principales: Green, James A, Yang, Jun, Grati, M’hamed, Kachar, Bechara, Bhat, Manzoor A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844453/
https://www.ncbi.nlm.nih.gov/pubmed/24011083
http://dx.doi.org/10.1186/1471-2202-14-96