Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP(2) in dorsal root ganglia neurons

BACKGROUND: Rapamycin-induced translocation systems can be used to manipulate biological processes with precise temporal control. These systems are based on rapamycin-induced dimerization of FK506 Binding Protein 12 (FKBP12) with the FKBP Rapamycin Binding (FRB) domain of mammalian target of rapamyc...

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Detalles Bibliográficos
Autores principales: Coutinho-Budd, Jaeda C, Snider, Samuel B, Fitzpatrick, Brendan J, Rittiner, Joseph E, Zylka, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844522/
https://www.ncbi.nlm.nih.gov/pubmed/24010830
http://dx.doi.org/10.1186/1477-5751-12-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844522/
https://www.ncbi.nlm.nih.gov/pubmed/24010830
http://dx.doi.org/10.1186/1477-5751-12-13

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