Transcriptional downregulation of S1pr1 is required for establishment of resident memory CD8(+) T cells

Cell-mediated immunity critically depends on lymphocyte localization at sites of infection. While some memory T cells recirculate, a distinct lineage (resident memory T cells; T(RM)) are embedded in non-lymphoid tissues (NLTs) and mediate potent protective immunity. However, the defining transcripti...

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Detalles Bibliográficos
Autores principales: Skon, Cara N., Lee, June-Yong, Anderson, Kristin G., Masopust, David, Hogquist, Kristin A., Jameson, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844557/
https://www.ncbi.nlm.nih.gov/pubmed/24162775
http://dx.doi.org/10.1038/ni.2745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844557/
https://www.ncbi.nlm.nih.gov/pubmed/24162775
http://dx.doi.org/10.1038/ni.2745

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