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The effect of metformin on apoptosis in a breast cancer presurgical trial

BACKGROUND: Metformin has been associated with antitumour activity in breast cancer (BC) but its mechanism remains unclear. We determined whether metformin induced a modulation of apoptosis by terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) overall and by insulin resistance sta...

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Detalles Bibliográficos
Autores principales:	Cazzaniga, M, DeCensi, A, Pruneri, G, Puntoni, M, Bottiglieri, L, Varricchio, C, Guerrieri-Gonzaga, A, Gentilini, O D, Pagani, G, Dell'Orto, P, Lazzeroni, M, Serrano, D, Viale, G, Bonanni, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844911/ https://www.ncbi.nlm.nih.gov/pubmed/24157825 http://dx.doi.org/10.1038/bjc.2013.657

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