Transcriptional Protein-Protein Cooperativity in POU/HMG/DNA Complexes Revealed by Normal Mode Analysis

Biomolecular cooperativity is of great scientific interest due to its role in biological processes. Two transcription factors (TFs), Oct-4 and Sox-2, are crucial in transcriptional regulation of embryonic stem cells. In this paper, we analyze how Oct-1 (a similar POU factor) and Sox-2, interact coop...

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Detalles Bibliográficos
Autores principales: Wang, Debby D., Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845252/
https://www.ncbi.nlm.nih.gov/pubmed/24324527
http://dx.doi.org/10.1155/2013/854710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845252/
https://www.ncbi.nlm.nih.gov/pubmed/24324527
http://dx.doi.org/10.1155/2013/854710

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