Mechanism of chiral proofreading during translation of the genetic code

The biological macromolecular world is homochiral and effective enforcement and perpetuation of this homochirality is essential for cell survival. In this study, we present the mechanistic basis of a configuration-specific enzyme that selectively removes D-amino acids erroneously coupled to tRNAs. T...

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Detalles Bibliográficos
Autores principales: Ahmad, Sadeem, Routh, Satya Brata, Kamarthapu, Venu, Chalissery, Jisha, Muthukumar, Sowndarya, Hussain, Tanweer, Kruparani, Shobha P, Deshmukh, Mandar V, Sankaranarayanan, Rajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845328/
https://www.ncbi.nlm.nih.gov/pubmed/24302572
http://dx.doi.org/10.7554/eLife.01519

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