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Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute

Purpose. To compare the diagnostic accuracy of hepatospecific contrast-enhanced MRI versus triple-phase CT scan after radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Methods. Thirty-four consecutive HCC patients (42 hepatic nodules) were treated with percutaneous RFA and un...

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Autores principales: Granata, Vincenza, Petrillo, Mario, Fusco, Roberta, Setola, Sergio Venanzio, de Lutio di Castelguidone, Elisabetta, Catalano, Orlando, Piccirillo, Mauro, Albino, Vittorio, Izzo, Francesco, Petrillo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845503/
https://www.ncbi.nlm.nih.gov/pubmed/24324487
http://dx.doi.org/10.1155/2013/469097
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author Granata, Vincenza
Petrillo, Mario
Fusco, Roberta
Setola, Sergio Venanzio
de Lutio di Castelguidone, Elisabetta
Catalano, Orlando
Piccirillo, Mauro
Albino, Vittorio
Izzo, Francesco
Petrillo, Antonella
author_facet Granata, Vincenza
Petrillo, Mario
Fusco, Roberta
Setola, Sergio Venanzio
de Lutio di Castelguidone, Elisabetta
Catalano, Orlando
Piccirillo, Mauro
Albino, Vittorio
Izzo, Francesco
Petrillo, Antonella
author_sort Granata, Vincenza
collection PubMed
description Purpose. To compare the diagnostic accuracy of hepatospecific contrast-enhanced MRI versus triple-phase CT scan after radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Methods. Thirty-four consecutive HCC patients (42 hepatic nodules) were treated with percutaneous RFA and underwent MR and CT scans. All patients were enrolled in a research protocol that included CT with iodized contrast medium injection and MR with hepatospecific contrast medium injection. All patients were restaged within four weeks and at 3 months from ablation. The images were reviewed by four different radiologists to evaluate tumor necrosis, residual or recurrence disease, and evidence of new foci. Results. Thirty-two nodules were necrotic after treatment; 10 showed residual disease. Six new HCCs were identified. At first month followup CT has identified 34 necrotic lesions and 8 residual diseases; no new foci were recognized. At MRI instead, 32 complete necrotic lesions were identified, 10 lesions showed residual disease, and 2 new HCCs were found. At three months, CT demonstrated 33 completely necrotic lesions, 9 residual diseases, and 2 new HCCs. MR showed 31 complete necrotic lesions, 11 cases of residual disease, and 6 new HCCs. Conclusions. Hepatospecific contrast-enhanced MRI is more effective than multiphase CT in assessment of HCC treated with RFA.
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spelling pubmed-38455032013-12-09 Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute Granata, Vincenza Petrillo, Mario Fusco, Roberta Setola, Sergio Venanzio de Lutio di Castelguidone, Elisabetta Catalano, Orlando Piccirillo, Mauro Albino, Vittorio Izzo, Francesco Petrillo, Antonella Gastroenterol Res Pract Clinical Study Purpose. To compare the diagnostic accuracy of hepatospecific contrast-enhanced MRI versus triple-phase CT scan after radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Methods. Thirty-four consecutive HCC patients (42 hepatic nodules) were treated with percutaneous RFA and underwent MR and CT scans. All patients were enrolled in a research protocol that included CT with iodized contrast medium injection and MR with hepatospecific contrast medium injection. All patients were restaged within four weeks and at 3 months from ablation. The images were reviewed by four different radiologists to evaluate tumor necrosis, residual or recurrence disease, and evidence of new foci. Results. Thirty-two nodules were necrotic after treatment; 10 showed residual disease. Six new HCCs were identified. At first month followup CT has identified 34 necrotic lesions and 8 residual diseases; no new foci were recognized. At MRI instead, 32 complete necrotic lesions were identified, 10 lesions showed residual disease, and 2 new HCCs were found. At three months, CT demonstrated 33 completely necrotic lesions, 9 residual diseases, and 2 new HCCs. MR showed 31 complete necrotic lesions, 11 cases of residual disease, and 6 new HCCs. Conclusions. Hepatospecific contrast-enhanced MRI is more effective than multiphase CT in assessment of HCC treated with RFA. Hindawi Publishing Corporation 2013 2013-11-12 /pmc/articles/PMC3845503/ /pubmed/24324487 http://dx.doi.org/10.1155/2013/469097 Text en Copyright © 2013 Vincenza Granata et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Granata, Vincenza
Petrillo, Mario
Fusco, Roberta
Setola, Sergio Venanzio
de Lutio di Castelguidone, Elisabetta
Catalano, Orlando
Piccirillo, Mauro
Albino, Vittorio
Izzo, Francesco
Petrillo, Antonella
Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title_full Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title_fullStr Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title_full_unstemmed Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title_short Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
title_sort surveillance of hcc patients after liver rfa: role of mri with hepatospecific contrast versus three-phase ct scan—experience of high volume oncologic institute
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845503/
https://www.ncbi.nlm.nih.gov/pubmed/24324487
http://dx.doi.org/10.1155/2013/469097
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