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The calcitonin gene-related peptide receptor antagonist MK-8825 decreases spinal trigeminal activity during nitroglycerin infusion

BACKGROUND: Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) are regarded as key mediators in migraine and other primary headaches. Migraineurs respond to infusion of nitroglycerin with delayed headaches, and inhibition of CGRP receptors has been shown to be effective in migraine therapy...

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Detalles Bibliográficos
Autores principales:	Feistel, Stephan, Albrecht, Stephanie, Messlinger, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845525/ https://www.ncbi.nlm.nih.gov/pubmed/24256609 http://dx.doi.org/10.1186/1129-2377-14-93

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