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IGF-1R as an anti-cancer target—trials and tribulations
Type I insulin-like growth factor receptor (IGF-1R) has long been recognized for its role in tumorigenesis and growth, but only recently have the tools for targeting the IGF pathway become available. More than 10 IGF/IGF-1R inhibitors have entered clinical trials, and these belong to three main clas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Sun Yat-sen University Cancer Center
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845553/ https://www.ncbi.nlm.nih.gov/pubmed/23601239 http://dx.doi.org/10.5732/cjc.012.10263 |