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Small nucleolar RNAs (snoRNAs) as potential non-invasive biomarkers for early cancer detection

Small nucleolar RNAs (snoRNAs) are non-coding RNA (ncRNA) molecules, which are associated with specific proteins to form small nucleolar ribonucleoparticles. However, the function of snoRNAs in cancer still remains elusive. Recently, several independent lines of evidence have indicated that these nc...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Dan, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845616/
https://www.ncbi.nlm.nih.gov/pubmed/23237223
http://dx.doi.org/10.5732/cjc.012.10132
Descripción
Sumario:Small nucleolar RNAs (snoRNAs) are non-coding RNA (ncRNA) molecules, which are associated with specific proteins to form small nucleolar ribonucleoparticles. However, the function of snoRNAs in cancer still remains elusive. Recently, several independent lines of evidence have indicated that these ncRNAs might have crucial roles in controlling tumorigenesis, and snoRNAs could be potential biomarkers for cancer.