Cargando…

An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family

Recurrent viral pressure has acted on host-encoded antiviral genes during primate and mammalian evolution. This selective pressure has resulted in dramatic episodes of adaptation in host antiviral genes, often detected via positive selection. These evolutionary signatures of adaptation have the pote...

Descripción completa

Detalles Bibliográficos
Autores principales: Malfavon-Borja, Ray, Sawyer, Sara L., Wu, Lily I., Emerman, Michael, Malik, Harmit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845644/
https://www.ncbi.nlm.nih.gov/pubmed/24158625
http://dx.doi.org/10.1093/gbe/evt163