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An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family
Recurrent viral pressure has acted on host-encoded antiviral genes during primate and mammalian evolution. This selective pressure has resulted in dramatic episodes of adaptation in host antiviral genes, often detected via positive selection. These evolutionary signatures of adaptation have the pote...
Autores principales: | Malfavon-Borja, Ray, Sawyer, Sara L., Wu, Lily I., Emerman, Michael, Malik, Harmit S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845644/ https://www.ncbi.nlm.nih.gov/pubmed/24158625 http://dx.doi.org/10.1093/gbe/evt163 |
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