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The RASSF1 Gene and the Opposing Effects of the RASSF1A and RASSF1C Isoforms on Cell Proliferation and Apoptosis

RASSF1A has been demonstrated to be a tumor suppressor, while RASSF1C is now emerging as a growth promoting protein in breast and lung cancer cells. To further highlight the dual functionality of the RASSF1 gene, we have compared the effects of RASSF1A and RASSF1C on cell proliferation and apoptosis...

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Detalles Bibliográficos
Autores principales: Reeves, Mark E., Firek, Matthew, Chen, Shin-Tai, Amaar, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845702/
https://www.ncbi.nlm.nih.gov/pubmed/24327924
http://dx.doi.org/10.1155/2013/145096