Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2

The long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs)—eicosapentaenoic acid (EPA) and its metabolite docosahexaenoic acid (DHA)—inhibit cancer formation in vivo, but their mechanism of action is unclear. Extracellular signal-regulated kinase 1/2 (ERK1/2) activation and inhibition have both...

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Detalles Bibliográficos
Autores principales: Nikolakopoulou, Zacharoula, Nteliopoulos, Georgios, Michael-Titus, Adina T., Parkinson, Eric Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845892/
https://www.ncbi.nlm.nih.gov/pubmed/23892603
http://dx.doi.org/10.1093/carcin/bgt257

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