PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1

BACKGROUND: Stroke severity is worsened by recruitment of inflammatory immune cells into the brain. This process depends in part on T cell activation, in which the B7 family of co-stimulatory molecules plays a pivotal role. Previous studies demonstrated more severe infarcts in mice lacking programme...

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Detalles Bibliográficos
Autores principales: Bodhankar, Sheetal, Chen, Yingxin, Vandenbark, Arthur A, Murphy, Stephanie J, Offner, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846120/
https://www.ncbi.nlm.nih.gov/pubmed/24015822
http://dx.doi.org/10.1186/1742-2094-10-111

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