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Audiological Manifestations in Vitiligo Patients
INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846206/ https://www.ncbi.nlm.nih.gov/pubmed/24303383 |
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author | Mahdi, Parvane Rouzbahani, Masomeh Amali, Amin Rezaii Khiabanlu, Samad Kamali, Mohammad |
author_facet | Mahdi, Parvane Rouzbahani, Masomeh Amali, Amin Rezaii Khiabanlu, Samad Kamali, Mohammad |
author_sort | Mahdi, Parvane |
collection | PubMed |
description | INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body and not just the skin. The purpose of this study was to assess the incidence of auditory alterations in patients with vitiligo MATERIALS AND METHODS: A total of 21 patients diagnosed with vitiligo were enrolled in this study. A group of 20 healthy subjects served as a control group. Pure tone audiometry (PTA) and measurements of auditory brain stem responses (ABR) were carried out in all participants. RESULTS: High frequency sensory neural hearing loss was detected in 8 patients (38.09%). Analysis of ABR revealed that 10 patients (47.61%) had an abnormal increase in the latency of Wave III and 6 (28.57%) had an abnormal prolongation of the inter peak latency between Wave I and III. There was no correlation between age, duration of disease, and any of the recorded parameters. CONCLUSION: This study highlights the involvement of the auditory system in patients with vitiligo, suggesting that vitiligo is a systemic disease rather than a purely cutaneous problem. |
format | Online Article Text |
id | pubmed-3846206 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-38462062013-12-03 Audiological Manifestations in Vitiligo Patients Mahdi, Parvane Rouzbahani, Masomeh Amali, Amin Rezaii Khiabanlu, Samad Kamali, Mohammad Iran J Otorhinolaryngol Original Article INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body and not just the skin. The purpose of this study was to assess the incidence of auditory alterations in patients with vitiligo MATERIALS AND METHODS: A total of 21 patients diagnosed with vitiligo were enrolled in this study. A group of 20 healthy subjects served as a control group. Pure tone audiometry (PTA) and measurements of auditory brain stem responses (ABR) were carried out in all participants. RESULTS: High frequency sensory neural hearing loss was detected in 8 patients (38.09%). Analysis of ABR revealed that 10 patients (47.61%) had an abnormal increase in the latency of Wave III and 6 (28.57%) had an abnormal prolongation of the inter peak latency between Wave I and III. There was no correlation between age, duration of disease, and any of the recorded parameters. CONCLUSION: This study highlights the involvement of the auditory system in patients with vitiligo, suggesting that vitiligo is a systemic disease rather than a purely cutaneous problem. Mashhad University of Medical Sciences 2012 /pmc/articles/PMC3846206/ /pubmed/24303383 Text en © 2012: Iranian Journal of Otorhinolaryngology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mahdi, Parvane Rouzbahani, Masomeh Amali, Amin Rezaii Khiabanlu, Samad Kamali, Mohammad Audiological Manifestations in Vitiligo Patients |
title | Audiological Manifestations in Vitiligo Patients |
title_full | Audiological Manifestations in Vitiligo Patients |
title_fullStr | Audiological Manifestations in Vitiligo Patients |
title_full_unstemmed | Audiological Manifestations in Vitiligo Patients |
title_short | Audiological Manifestations in Vitiligo Patients |
title_sort | audiological manifestations in vitiligo patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846206/ https://www.ncbi.nlm.nih.gov/pubmed/24303383 |
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