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Audiological Manifestations in Vitiligo Patients

INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body an...

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Autores principales: Mahdi, Parvane, Rouzbahani, Masomeh, Amali, Amin, Rezaii Khiabanlu, Samad, Kamali, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846206/
https://www.ncbi.nlm.nih.gov/pubmed/24303383
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author Mahdi, Parvane
Rouzbahani, Masomeh
Amali, Amin
Rezaii Khiabanlu, Samad
Kamali, Mohammad
author_facet Mahdi, Parvane
Rouzbahani, Masomeh
Amali, Amin
Rezaii Khiabanlu, Samad
Kamali, Mohammad
author_sort Mahdi, Parvane
collection PubMed
description INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body and not just the skin. The purpose of this study was to assess the incidence of auditory alterations in patients with vitiligo MATERIALS AND METHODS: A total of 21 patients diagnosed with vitiligo were enrolled in this study. A group of 20 healthy subjects served as a control group. Pure tone audiometry (PTA) and measurements of auditory brain stem responses (ABR) were carried out in all participants. RESULTS: High frequency sensory neural hearing loss was detected in 8 patients (38.09%). Analysis of ABR revealed that 10 patients (47.61%) had an abnormal increase in the latency of Wave III and 6 (28.57%) had an abnormal prolongation of the inter peak latency between Wave I and III. There was no correlation between age, duration of disease, and any of the recorded parameters. CONCLUSION: This study highlights the involvement of the auditory system in patients with vitiligo, suggesting that vitiligo is a systemic disease rather than a purely cutaneous problem.
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spelling pubmed-38462062013-12-03 Audiological Manifestations in Vitiligo Patients Mahdi, Parvane Rouzbahani, Masomeh Amali, Amin Rezaii Khiabanlu, Samad Kamali, Mohammad Iran J Otorhinolaryngol Original Article INTRODUCTION: The hallmark of vitiligo is the disappearance of melanocytes from the skin due to an as yet unidentified mechanism. The presence of melanocytes in the auditory apparatus suggests that this system could possibly be affected by vitiligo, which targets the melanocytes of the whole body and not just the skin. The purpose of this study was to assess the incidence of auditory alterations in patients with vitiligo MATERIALS AND METHODS: A total of 21 patients diagnosed with vitiligo were enrolled in this study. A group of 20 healthy subjects served as a control group. Pure tone audiometry (PTA) and measurements of auditory brain stem responses (ABR) were carried out in all participants. RESULTS: High frequency sensory neural hearing loss was detected in 8 patients (38.09%). Analysis of ABR revealed that 10 patients (47.61%) had an abnormal increase in the latency of Wave III and 6 (28.57%) had an abnormal prolongation of the inter peak latency between Wave I and III. There was no correlation between age, duration of disease, and any of the recorded parameters. CONCLUSION: This study highlights the involvement of the auditory system in patients with vitiligo, suggesting that vitiligo is a systemic disease rather than a purely cutaneous problem. Mashhad University of Medical Sciences 2012 /pmc/articles/PMC3846206/ /pubmed/24303383 Text en © 2012: Iranian Journal of Otorhinolaryngology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mahdi, Parvane
Rouzbahani, Masomeh
Amali, Amin
Rezaii Khiabanlu, Samad
Kamali, Mohammad
Audiological Manifestations in Vitiligo Patients
title Audiological Manifestations in Vitiligo Patients
title_full Audiological Manifestations in Vitiligo Patients
title_fullStr Audiological Manifestations in Vitiligo Patients
title_full_unstemmed Audiological Manifestations in Vitiligo Patients
title_short Audiological Manifestations in Vitiligo Patients
title_sort audiological manifestations in vitiligo patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846206/
https://www.ncbi.nlm.nih.gov/pubmed/24303383
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