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Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice

INTRODUCTION: The management and use of antimicrobial drugs has clinical, economic, and environmental implications. In many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. Therefore, health-care policy should focus on how to establish a rational attitude toward...

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Autores principales: Khatami-Moghadam, Minoo, Khorsandi-Ashtiani, Mohammad-Taghi, Mohagheghi, Mohammad-Ali, Hasibi, Mehrdad, Kouhi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846211/
https://www.ncbi.nlm.nih.gov/pubmed/24303390
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author Khatami-Moghadam, Minoo
Khorsandi-Ashtiani, Mohammad-Taghi
Mohagheghi, Mohammad-Ali
Hasibi, Mehrdad
Kouhi, Ali
author_facet Khatami-Moghadam, Minoo
Khorsandi-Ashtiani, Mohammad-Taghi
Mohagheghi, Mohammad-Ali
Hasibi, Mehrdad
Kouhi, Ali
author_sort Khatami-Moghadam, Minoo
collection PubMed
description INTRODUCTION: The management and use of antimicrobial drugs has clinical, economic, and environmental implications. In many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. Therefore, health-care policy should focus on how to establish a rational attitude toward antibiotics. This study was performed to investigate antibiotic usage as a prophylactic regimen in head and neck surgeries. MATERIALS AND METHODS: This study was a retrospective case series. Patients undergoing otolaryngology surgeries in a tertiary referral otolaryngology center were included. Members of operating room staff that were unaware of the study objectives collected patients’ data using a questionnaire that contained information regarding general medical condition, disease, surgical procedure, and prophylaxis regimen and duration. RESULTS: Excluding infected patients, we studied 1349 patients during a four-month period who needed prophylactic antibiotics. A total of 34 different types of surgical procedures were performed. Out of the total number of patients, 503 (37.0%) received a parenteral antibiotic directly before surgery. The main antibiotics used before surgery were cephalosporins (94.9%). All of the 1349 patients were administered antibiotics after the procedure. These antibiotics where given with a mean number of doses of 4.81 (range: 1–68), and also consisted of mostly cephalosporins. CONCLUSION: Our results indicate that prophylactic antibiotics were being significantly misused in a tertiary referral center of a university hospital. Although teaching the principles of prophylaxis to physicians is important, we think that finding a way to bring this knowledge to practice is more important.
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spelling pubmed-38462112013-12-03 Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice Khatami-Moghadam, Minoo Khorsandi-Ashtiani, Mohammad-Taghi Mohagheghi, Mohammad-Ali Hasibi, Mehrdad Kouhi, Ali Iran J Otorhinolaryngol Original Article INTRODUCTION: The management and use of antimicrobial drugs has clinical, economic, and environmental implications. In many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. Therefore, health-care policy should focus on how to establish a rational attitude toward antibiotics. This study was performed to investigate antibiotic usage as a prophylactic regimen in head and neck surgeries. MATERIALS AND METHODS: This study was a retrospective case series. Patients undergoing otolaryngology surgeries in a tertiary referral otolaryngology center were included. Members of operating room staff that were unaware of the study objectives collected patients’ data using a questionnaire that contained information regarding general medical condition, disease, surgical procedure, and prophylaxis regimen and duration. RESULTS: Excluding infected patients, we studied 1349 patients during a four-month period who needed prophylactic antibiotics. A total of 34 different types of surgical procedures were performed. Out of the total number of patients, 503 (37.0%) received a parenteral antibiotic directly before surgery. The main antibiotics used before surgery were cephalosporins (94.9%). All of the 1349 patients were administered antibiotics after the procedure. These antibiotics where given with a mean number of doses of 4.81 (range: 1–68), and also consisted of mostly cephalosporins. CONCLUSION: Our results indicate that prophylactic antibiotics were being significantly misused in a tertiary referral center of a university hospital. Although teaching the principles of prophylaxis to physicians is important, we think that finding a way to bring this knowledge to practice is more important. Mashhad University of Medical Sciences 2012 /pmc/articles/PMC3846211/ /pubmed/24303390 Text en © 2012: Iranian Journal of Otorhinolaryngology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Khatami-Moghadam, Minoo
Khorsandi-Ashtiani, Mohammad-Taghi
Mohagheghi, Mohammad-Ali
Hasibi, Mehrdad
Kouhi, Ali
Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title_full Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title_fullStr Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title_full_unstemmed Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title_short Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice
title_sort prophylactic antibiotics in otolaryngologic surgeries: from knowledge to practice
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846211/
https://www.ncbi.nlm.nih.gov/pubmed/24303390
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