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Automated analysis of immunoglobulin genes from high-throughput sequencing: life without a template

BACKGROUND: Immunoglobulin (that is, antibody) and T cell receptor genes are created through somatic gene rearrangement from gene segment libraries. Immunoglobulin genes are further diversified by somatic hypermutation and selection during the immune response. Studying the repertoires of these genes...

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Detalles Bibliográficos
Autores principales:	Michaeli, Miri, Barak, Michal, Hazanov, Lena, Noga, Hila, Mehr, Ramit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846367/ https://www.ncbi.nlm.nih.gov/pubmed/23977981 http://dx.doi.org/10.1186/2043-9113-3-15

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