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Mice with RyR1 mutation (Y524S) undergo hypermetabolic response to simvastatin

BACKGROUND: Statins are widely used drugs for the treatment of hyperlipidemia. Though relatively safe, some individuals taking statins experience rhabdymyolysis, muscle pain, and cramping, a condition termed statin-induced myopathy (SIM). To determine if mutations in the skeletal muscle calcium (Ca(...

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Detalles Bibliográficos
Autores principales:	Knoblauch, Mark, Dagnino-Acosta, Adan, Hamilton, Susan L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846650/ https://www.ncbi.nlm.nih.gov/pubmed/24004537 http://dx.doi.org/10.1186/2044-5040-3-22

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