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A Balanced IL-1β Activity Is Required for Host Response to Citrobacter rodentium Infection

Microbial sensing plays essential roles in the innate immune response to pathogens. In particular, NLRP3 forms a multiprotein inflammasome complex responsible for the maturation of interleukin (IL)-1β. Our aim was to delineate the role of the NLRP3 inflammasome in macrophages, and the contribution o...

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Detalles Bibliográficos
Autores principales:	Alipour, Misagh, Lou, Yuefei, Zimmerman, Daniel, Bording-Jorgensen, Michael W., Sergi, Consolato, Liu, Julia J., Wine, Eytan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846666/ https://www.ncbi.nlm.nih.gov/pubmed/24312491 http://dx.doi.org/10.1371/journal.pone.0080656

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