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The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling

BACKGROUND: The eyes and skin are obvious retinoid target organs. Vitamin A deficiency causes night blindness and retinoids are widely used to treat acne and psoriasis. However, more than 90% of total body retinol is stored in liver stellate cells. In addition, hepatocytes produce the largest amount...

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Detalles Bibliográficos
Autores principales: He, Yuqi, Gong, Lei, Fang, Yaping, Zhan, Qi, Liu, Hui-Xin, Lu, Yanliu, Guo, Grace L, Lehman-McKeeman, Lois, Fang, Jianwen, Wan, Yu-Jui Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846674/
https://www.ncbi.nlm.nih.gov/pubmed/23981290
http://dx.doi.org/10.1186/1471-2164-14-575