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Evaluation of the Stability, Bioavailability, and Hypersensitivity of the Omega-3 Derived Anti-Leukemic Prostaglandin: Δ(12)-Prostaglandin J(3)
Previous studies have demonstrated the ability of an eicosapentaenoic acid (EPA)-derived endogenous cyclopentenone prostaglandin (CyPG) metabolite, Δ(12)-PGJ(3), to selectively target leukemic stem cells, but not the normal hematopoietic stems cells, in in vitro and in vivo models of chronic myeloge...
Autores principales: | Kudva, Avinash K., Kaushal, Naveen, Mohinta, Sonia, Kennett, Mary J., August, Avery, Paulson, Robert F., Prabhu, K. Sandeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846793/ https://www.ncbi.nlm.nih.gov/pubmed/24312486 http://dx.doi.org/10.1371/journal.pone.0080622 |
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