Cargando…
Discovery of a Mammalian Splice Variant of Myostatin That Stimulates Myogenesis
Myostatin plays a fundamental role in regulating the size of skeletal muscles. To date, only a single myostatin gene and no splice variants have been identified in mammals. Here we describe the splicing of a cryptic intron that removes the coding sequence for the receptor binding moiety of sheep myo...
Autores principales: | Jeanplong, Ferenc, Falconer, Shelley J., Oldham, Jenny M., Thomas, Mark, Gray, Tarra S., Hennebry, Alex, Matthews, Kenneth G., Kemp, Frederick C., Patel, Ketan, Berry, Carole, Nicholas, Gina, McMahon, Christopher D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846833/ https://www.ncbi.nlm.nih.gov/pubmed/24312578 http://dx.doi.org/10.1371/journal.pone.0081713 |
Ejemplares similares
-
Translational Signalling, Atrogenic and Myogenic Gene Expression during Unloading and Reloading of Skeletal Muscle in Myostatin-Deficient Mice
por: Smith, Heather K., et al.
Publicado: (2014) -
Systematic Myostatin Expression Screening Platform for Identification and Evaluation of Myogenesis-Related Phytogenic in Pigs
por: Ou, Bor-Rung, et al.
Publicado: (2023) -
CARP, a Myostatin-downregulated Gene in CFM Cells, Is a Novel Essential Positive Regulator of Myogenesis
por: Ma, Guoda, et al.
Publicado: (2014) -
A novel splice variant of the human MSTN gene encodes a myostatin‐specific myostatin inhibitor
por: Maeta, Kazuhiro, et al.
Publicado: (2023) -
Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle
por: Tsao, James, et al.
Publicado: (2013)