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A Mathematical Model of the Enhanced Permeability and Retention Effect for Liposome Transport in Solid Tumors
The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...
Autores principales: | Stapleton, Shawn, Milosevic, Michael, Allen, Christine, Zheng, Jinzi, Dunne, Michael, Yeung, Ivan, Jaffray, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846845/ https://www.ncbi.nlm.nih.gov/pubmed/24312530 http://dx.doi.org/10.1371/journal.pone.0081157 |
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