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Impressive thrombocytosis evolving in a patient with a BCR-ABL positive CML in major molecular response during dasatinib treatment unmasks an additional JAK2V617F

We present a case of a 42-year old female with the rare diagnosis of a myeloproliferative syndrome harboring both a BCR-ABL transclocation and a JAK2V617F mutation. Initially diagnosed with a CML, the patient underwent treatment with imatinib followed by dasatinib. Despite a major molecular response...

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Detalles Bibliográficos
Autores principales: Pastore, Friederike, Schneider, Stephanie, Christ, Oliver, Hiddemann, Wolfgang, Spiekermann, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847069/
https://www.ncbi.nlm.nih.gov/pubmed/24007855
http://dx.doi.org/10.1186/2162-3619-2-24

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