Synergistic Interactions between Alzheimer’s Aβ40 and Aβ42 on the Surface of Primary Neurons Revealed by Single Molecule Microscopy

Two amyloid-β peptides (Aβ40 and Aβ42) feature prominently in the extracellular brain deposits associated with Alzheimer’s disease. While Aβ40 is the prevalent form in the cerebrospinal fluid, the fraction of Aβ42 increases in the amyloid deposits over the course of disease development. The low in v...

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Detalles Bibliográficos
Autores principales: Chang, Chun-Chieh, Althaus, John Christian, Carruthers, Cynthia J. L., Sutton, Michael A., Steel, Duncan G., Gafni, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847093/
https://www.ncbi.nlm.nih.gov/pubmed/24312636
http://dx.doi.org/10.1371/journal.pone.0082139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847093/
https://www.ncbi.nlm.nih.gov/pubmed/24312636
http://dx.doi.org/10.1371/journal.pone.0082139

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