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Biochemical and immunological mechanisms by which sickle cell trait protects against malaria

Sickle cell trait (HbAS) is the best-characterized genetic polymorphism known to protect against falciparum malaria. Although the protective effect of HbAS against malaria is well known, the mechanism(s) of protection remain unclear. A number of biochemical and immune-mediated mechanisms have been p...

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Detalles Bibliográficos
Autores principales:	Gong, Lauren, Parikh, Sunil, Rosenthal, Philip J, Greenhouse, Bryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847285/ https://www.ncbi.nlm.nih.gov/pubmed/24025776 http://dx.doi.org/10.1186/1475-2875-12-317

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