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Diacylglycerol metabolism attenuates T-cell receptor signaling and alters thymocyte differentiation

Diacylglycerol (DAG) metabolism has a critical function in Ras-regulated functions in mature T cells, but causal data linking defects in DAG-based signals with altered thymus development are missing. To study the effect of increased DAG metabolism in T-cell development, we engineered a membrane-targ...

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Detalles Bibliográficos
Autores principales:	Almena, M, Andrada, E, Liebana, R, Merida, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847306/ https://www.ncbi.nlm.nih.gov/pubmed/24201811 http://dx.doi.org/10.1038/cddis.2013.396

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