Role of the p63-FoxN1 regulatory axis in thymic epithelial cell homeostasis during aging

The p63 gene regulates thymic epithelial cell (TEC) proliferation, whereas FoxN1 regulates their differentiation. However, their collaborative role in the regulation of TEC homeostasis during thymic aging is largely unknown. In murine models, the proportion of TAp63(+), but not ΔNp63(+), TECs was in...

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Detalles Bibliográficos
Autores principales: Burnley, P, Rahman, M, Wang, H, Zhang, Z, Sun, X, Zhuge, Q, Su, D-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847336/
https://www.ncbi.nlm.nih.gov/pubmed/24263106
http://dx.doi.org/10.1038/cddis.2013.460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847336/
https://www.ncbi.nlm.nih.gov/pubmed/24263106
http://dx.doi.org/10.1038/cddis.2013.460

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