The dopamine D(1) receptor is expressed and facilitates relaxation in airway smooth muscle

BACKGROUND: Dopamine signaling is mediated by G(s) protein-coupled “D(1)-like” receptors (D(1) and D(5)) and G(i)-coupled “D(2)-like” receptors (D(2-4)). In asthmatic patients, inhaled dopamine induces bronchodilation. Although the G(i)-coupled dopamine D(2) receptor is expressed and sensitizes aden...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizuta, Kentaro, Zhang, Yi, Xu, Dingbang, Mizuta, Fumiko, D’Ovidio, Frank, Masaki, Eiji, Emala, Charles W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847358/
https://www.ncbi.nlm.nih.gov/pubmed/24004608
http://dx.doi.org/10.1186/1465-9921-14-89

Ejemplares similares

Ejemplares similares