BetaHCG secretion by a pulmonary adenocarcinoma

We report a rare case of metastatic non-small-cell lung cancer in a 43-year-old woman with a history of smoking. The tumor secreted human chorionic gonadotropin and its beta subunit (BetaHCG). The patient presented with amenorrhea, a positive pregnancy test and chest pain. A physical examination and...

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Autores principales: Vicier, Cécile, Tabouret, Emeline, Tallet, Agnès, Gonçalves, Anthony, Chetaille, Bruno, Viens, Patrice, Madroszyk, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847484/
https://www.ncbi.nlm.nih.gov/pubmed/24034807
http://dx.doi.org/10.1186/1477-7819-11-228
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author Vicier, Cécile
Tabouret, Emeline
Tallet, Agnès
Gonçalves, Anthony
Chetaille, Bruno
Viens, Patrice
Madroszyk, Anne
author_facet Vicier, Cécile
Tabouret, Emeline
Tallet, Agnès
Gonçalves, Anthony
Chetaille, Bruno
Viens, Patrice
Madroszyk, Anne
author_sort Vicier, Cécile
collection PubMed
description We report a rare case of metastatic non-small-cell lung cancer in a 43-year-old woman with a history of smoking. The tumor secreted human chorionic gonadotropin and its beta subunit (BetaHCG). The patient presented with amenorrhea, a positive pregnancy test and chest pain. A physical examination and investigations revealed no pregnancy, and it was determined that a paraneoplastic syndrome stemming from a pulmonary tumor was responsible for the secretion of BetaHCG. This secretion decreased with tumor response to chemotherapy. Only a few reports of paraneoplastic BetaHCG secretion can be found in the literature for several different cancers.
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spelling pubmed-38474842013-12-04 BetaHCG secretion by a pulmonary adenocarcinoma Vicier, Cécile Tabouret, Emeline Tallet, Agnès Gonçalves, Anthony Chetaille, Bruno Viens, Patrice Madroszyk, Anne World J Surg Oncol Case Report We report a rare case of metastatic non-small-cell lung cancer in a 43-year-old woman with a history of smoking. The tumor secreted human chorionic gonadotropin and its beta subunit (BetaHCG). The patient presented with amenorrhea, a positive pregnancy test and chest pain. A physical examination and investigations revealed no pregnancy, and it was determined that a paraneoplastic syndrome stemming from a pulmonary tumor was responsible for the secretion of BetaHCG. This secretion decreased with tumor response to chemotherapy. Only a few reports of paraneoplastic BetaHCG secretion can be found in the literature for several different cancers. BioMed Central 2013-09-14 /pmc/articles/PMC3847484/ /pubmed/24034807 http://dx.doi.org/10.1186/1477-7819-11-228 Text en Copyright © 2013 Vicier et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Vicier, Cécile
Tabouret, Emeline
Tallet, Agnès
Gonçalves, Anthony
Chetaille, Bruno
Viens, Patrice
Madroszyk, Anne
BetaHCG secretion by a pulmonary adenocarcinoma
title BetaHCG secretion by a pulmonary adenocarcinoma
title_full BetaHCG secretion by a pulmonary adenocarcinoma
title_fullStr BetaHCG secretion by a pulmonary adenocarcinoma
title_full_unstemmed BetaHCG secretion by a pulmonary adenocarcinoma
title_short BetaHCG secretion by a pulmonary adenocarcinoma
title_sort betahcg secretion by a pulmonary adenocarcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847484/
https://www.ncbi.nlm.nih.gov/pubmed/24034807
http://dx.doi.org/10.1186/1477-7819-11-228
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AT chetaillebruno betahcgsecretionbyapulmonaryadenocarcinoma
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