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Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling

BACKGROUND: PCAF is an important intrinsic histone acetyltransferases. This study tried to establish the effect of PCAF on HCC cell apoptosis. METHOD: Both in vitro and in vivo experiments including IHC, DAPI staining, caspase 3/7 activity assay, BrdU assay, MTT assay, western immunoblotting and co-...

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Detalles Bibliográficos
Autores principales:	Zheng, Xin, Gai, Xiaohong, Ding, Feihu, Lu, Zhongtang, Tu, Kangsheng, Yao, Yingmin, Liu, Qingguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847488/ https://www.ncbi.nlm.nih.gov/pubmed/23981651 http://dx.doi.org/10.1186/1476-4598-12-96

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