Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: A Game of Stop and Go

The aim of therapeutic dendritic cell (DC) vaccines in cancer immunotherapy is to activate cytotoxic T cells to recognize and attack the tumor. T cell activation requires the interaction of the T cell receptor with a cognate major-histocompatibility complex-peptide complex. Although initiated by ant...

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Detalles Bibliográficos
Autores principales: Vasaturo, Angela, Di Blasio, Stefania, Peeters, Deborah G. A., de Koning, Coco C. H., de Vries, Jolanda M., Figdor, Carl G., Hato, Stanleyson V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847559/
https://www.ncbi.nlm.nih.gov/pubmed/24348481
http://dx.doi.org/10.3389/fimmu.2013.00417

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