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rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

BACKGROUND: Therapeutic gene transfer is of significant value to elaborate efficient, durable treatments against human osteoarthritis (OA), a slow, progressive, and irreversible disorder for which there is no cure to date. METHODS: Here, we directly applied a recombinant adeno-associated virus (rAAV...

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Detalles Bibliográficos
Autores principales:	Venkatesan, Jagadeesh K, Rey-Rico, Ana, Schmitt, Gertrud, Wezel, Anna, Madry, Henning, Cucchiarini, Magali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847562/ https://www.ncbi.nlm.nih.gov/pubmed/24034904 http://dx.doi.org/10.1186/1479-5876-11-211

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