Oral Toxicity of Okadaic Acid in Mice: Study of Lethality, Organ Damage, Distribution and Effects on Detoxifying Gene Expression

In vivo, after administration by gavage to mice and rats, okadaic acid has been reported to produce lesions in liver, small intestine and forestomach. Because several reports differ in the damage detected in different organs, and on okadaic acid distribution after consumption, we determined the toxi...

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Detalles Bibliográficos
Autores principales: Vieira, Andres C., Rubiolo, Juan A., López-Alonso, Henar, Cifuentes, José Manuel, Alfonso, Amparo, Bermúdez, Roberto, Otero, Paz, Vieytes, Mercedes R., Vega, Félix V., Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847716/
https://www.ncbi.nlm.nih.gov/pubmed/24217398
http://dx.doi.org/10.3390/toxins5112093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847716/
https://www.ncbi.nlm.nih.gov/pubmed/24217398
http://dx.doi.org/10.3390/toxins5112093

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