Identifying multiple causative genes at a single GWAS locus

Genome-wide association studies (GWAS) are useful for nominating candidate genes, but typically are unable to establish disease causality or differentiate between the effects of variants in linkage disequilibrium (LD). Additionally, some GWAS loci might contain multiple causative variants or genes t...

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Detalles Bibliográficos
Autores principales: Flister, Michael J., Tsaih, Shirng-Wern, O'Meara, Caitlin C., Endres, Bradley, Hoffman, Matthew J., Geurts, Aron M., Dwinell, Melinda R., Lazar, Jozef, Jacob, Howard J., Moreno, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847770/
https://www.ncbi.nlm.nih.gov/pubmed/24006081
http://dx.doi.org/10.1101/gr.160283.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847770/
https://www.ncbi.nlm.nih.gov/pubmed/24006081
http://dx.doi.org/10.1101/gr.160283.113

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