Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

Chromosome conformation capture approaches have shown that interphase chromatin is partitioned into spatially segregated Mb-sized compartments and sub-Mb-sized topological domains. This compartmentalization is thought to facilitate the matching of genes and regulatory elements, but its precise funct...

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Detalles Bibliográficos
Autores principales: Seitan, Vlad C., Faure, Andre J., Zhan, Ye, McCord, Rachel Patton, Lajoie, Bryan R., Ing-Simmons, Elizabeth, Lenhard, Boris, Giorgetti, Luca, Heard, Edith, Fisher, Amanda G., Flicek, Paul, Dekker, Job, Merkenschlager, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847776/
https://www.ncbi.nlm.nih.gov/pubmed/24002784
http://dx.doi.org/10.1101/gr.161620.113

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